Day: 03/10/2015

“Feeling detached from the world…”

http://lazarusandlithium.com/2015/03/05/day-6-of-partial-hospitalization-relapses-and-minor-profanities/

https://answers.yahoo.com/question/index?qid=20110211105952AAsrPnb

What “mental illness/disorder” does Donnie Darko have?  He is taking pills for Schizophrenia but he later finds out they are only placebo’s. The scene where his doctor tells him they are placebo’s is only in the director’s cut…

http://www.wordandfilm.com/2014/05/setting-stereotypes-straight-3-movies-about-mental-health/

Richard Kelly’s career-making 2001 surrealist science fiction masterpiece, “Donnie Darko,” features Jake Gyllenhaal as the titular character: a paranoid schizophrenic high school student troubled by visions of a sinister-looking figure in a rabbit costume named “Frank.” The end of the world is coming very soon, according to Frank, and Donnie may have something to do with it.

“Donnie Darko” has some very strong metaphysical leanings, and whether Donnie is truly schizophrenic is certainly open to interpretation, but his delusions, hallucinations, disorganized thoughts, erratic behavior, and blunted affect are all common symptoms of the disease. As the audience, we are privy to Donnie’s experiences and understand why he does the things that he does, but that doesn’t mean that Frank is real or that Donnie isn’t having a psychotic episode. Certainly, an outside observer would probably assume that he is. By making the viewer question reality, the film succeeds in communicating a vital aspect of schizophrenia.

“Hubby says marijuana makes me a better person.”

Daily Prompt Oh Surprise, More Weed Talk

In order to get certified for medical marijuana here, you need a year’s worth of medical records, a doctor’s letter, and then an appointment with a doctor that can certify you along with about $500. It’s a lot of expense and trouble. If you’re uncertain whether it will do you any good, your only option is to try to get some illegal pot off the street…

FDA keeps black box on Pfizer’s Chantix, adds new warning about alcohol

http://www.fiercepharma.com/story/fda-keeps-black-box-pfizers-chantix-adds-new-warning-about-alcohol/2015-03-10

Now, the agency has itself spoken. And it’s choosing not only to keep the black box, which highlights warnings about suicide and suicidal thoughts, but also to add new cautionary advice about Chantix’s interactions with alcohol. Some Chantix patients have reported unusual or aggressive behavior while drinking, the agency says. A few have experienced seizures…

Patients should cut down on alcohol when they start taking the drug, to see how they might react to the combination, the FDA says, because patients have reported decreased tolerance to alcohol…

10/11/2010, Barriers Remain for Primary Care Treatment of Addicts

It’s the only partial agonist approved for opioid addiction, but it’s comparable to varenicline (Chantix), a partial agonist for smoking cessation…

http://orca.cf.ac.uk/17939/

11/15/2013, Hypotension and bradycardia following varenicline overdose

Conclusion: Varenicline is a new drug and very little is known about its effects in overdose. This case suggests that toxicity may be seen at a dose which is relatively small compared to previously reported cases.

https://en.wikipedia.org/wiki/Bupropion

Marketed as Wellbutrin and Zyban, among other trade names, it is one of the most frequently prescribed antidepressants in the United States, although in many English-speaking countries, including the United Kingdom, Australia and New Zealand, this is an off-label use…

In any case, bupropion, via non-conventional routes of administration (e.g., injection, insufflation), is reported to be abused in Canada, and in recent years in United States prisons...

Opioid addiction drug for weight loss?

J&J pleads guilty, pays $20M fine tied to metal-tainted Children’s Tylenol

http://www.fiercepharma.com/story/jj-pleads-guilty-pays-20m-fine-tied-metal-tainted-childrens-tylenol/2015-03-10

The plea agreement announced by Justice Department and FDA officials today stemmed from a complaint that McNeil’s plant in Fort Washington, PA, received May 1, 2009, that there were black specks in some of its children’s pain medicines. But instead of starting an investigation to find out why, Johnson & Johnson ($JNJ) let it slide, according to the DOJ release.

The particles were later determined to be “nickel/chromium-rich inclusions” and not ingredients that should have been in the products taken by children throughout the world, court records indicate…

FDA Issues Warning Letters to CBD Hemp Oil Makers

http://www.hightimes.com/read/fda-issues-warning-letters-cbd-hemp-oil-makers

Anyone interested in getting cannabis flowers, extracts or infused products high in CBD should seek actual high-CBD cannabis (with CBD sometimes at more than 20 percent dry weight), not products made from industrial hemp. Cannabis bred for CBD and grown in healthy soils or in a clean hydroponic matrix is optimal for making safe medicinal products...