Real World Results Differ from Drug Studies

http://www.peoplespharmacy.com/2015/07/16/antidepressant-drug-studies-differ-from-the-real-world/

The result is that studies of antidepressants don’t really tell doctors or patients how well the drugs will work in real life. In fact, most antidepressants have a disappointing performance in clinical practice compared to how well they do in highly controlled clinical trials…

4 thoughts on “Real World Results Differ from Drug Studies

  1. I’m getting worried about all these latest studies showing antidepressants don’t work, because they’ve saved my life. I’ve also heard a few stories of other people who get the same spectacular overnight results I do.

    And, in case you think it’s placebo effect, they don’t all work. Wellbutrin and Effexor do, but they are the only ones. From cymbalta I thought I was losing my mind, and all the rest had no effect at all.

    I also assume only the placebo effect could explain my response, but why only for some? That makes no sense to me.

    Liked by 1 person

    • I guess I’m a little biased because antidepressants never worked for me, and I post a lot on the ineffectiveness of these drugs. But I believe they didn’t work for me because I don’t suffer from depression. I just want patients to be informed so they can make these decisions for themselves, and not have to depend on doctors.

      While I’m sure there’s a percentage of patients who are benefiting from the placebo effect, I’m also sure there’s a percentage of patients who are benefiting from the drugs themselves. And I don’t think you have anything to worry about — a patient’s choice for antidepressants is vast and here to stay.

      Liked by 1 person

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