Buprenorphine For Chronic Pain?

I found this in my Search Terms:  “2015 more doctors using buprenorphine for chronic pain”

Yes, it’s true, bupe (and Suboxone) are being used to treat chronic pain, although it’s mostly with the transdermal system, not in pill form.  There are different side effects with this type of delivery system, as explained by patients here:


It’s difficult to gauge the effectiveness of a pain medication when used in a placebo-controlled trial, even though that’s one of the only ways to obtain proof through “scientific evidence.” Seems almost cruel to make pain patients go without any type of pain medication throughout a research study.  This is one of the many reasons there isn’t any long-term studies on treating chronic pain with opioid therapy.


(2004) Transdermal buprenorphine in the treatment of chronic pain

Patients’ assessments of pain intensity and pain relief suggested better analgesia with buprenorphine TES than with placebo, although the differences did not reach statistical significance…


(2002) Analgesic efficacy and tolerability of transdermal buprenorphine in patients with inadequately controlled chronic pain related to cancer and other disorders

A total of 43.5% of patients treated with buprenorphine TDS reported good or complete pain relief compared with 32.4% in the placebo group…


Sat, 09/13/2008 – 7:38am #1
Anonymous (not verified)

Suboxone for Pain Mgmt
Anyone else taking Suboxone for pain?

My Pain Mgmt Dr. just started me on Suboxone on Monday afternoon for pain relief from DDD, Stenosis and sciatic flareup.

Is anyone else currently prescribed Suboxone for their pain? I was curious as to the level of pain relief you are having and also what if any side effects are troublesome?

At first I had some dizziness and general feeling of being “Out of it”. Hard to focus. That is getting better each day. However, I still have a feeling of being high. Pain relief is very good….better than Vicodin.

Richard J.

Sun, 09/28/2008 – 11:07pm #6

Oh there are most definately withdrawals from it they are just more subtle than with straight opiates. A lot of people at my rehab had trouble with getting off suboxone with no opiates being taken for months. For me yes it did help a bit with pain but I was going through hellish opiate withdrawals which is what its made to combat. Honestly though yes im sure it helps with pain maybe on the level of tramadol



6 thoughts on “Buprenorphine For Chronic Pain?

  1. You know I asked for Tramadol and was told no because it does not go with Cymbalta and may cause Serotonin whatever the rest of that is called. All I am taking for pain is Cymbalta (not helping much for physical pain, but great as an anti-depressant and Meloxicam. I know you brought up a few articles on Tramadol. This has nothing to do with this page.

    Liked by 1 person

      • Interesting read. Now I know why they were adamant about me taking it. I guess I was lucky because I took Tramadol for quite a while with some of those drugs and I didn’t have that problem. No I am not interested in medical canabis at this time anyhow. I understand the cost is quite prohibitive as well.

        Liked by 1 person

        • How long did you take Tramadol with an antidepressant or anti-psychotic? Seems to me that if you tolerated that combination before, your doctor should allow you to try it again, especially if it reduced your pain levels. However, I think the risk of Serotonin Syndrome is linked to how long you take this combination of drugs, so that might be a factor.

          Hydrocodone always worked pretty good for me, but that drug might be hard to get nowadays. Since I don’t have access to prescription drugs anymore, I’ve been using a lot of aspirin. It seems to help a little with the inflammation, but it can cause ulcers and stomach upset. Thankfully, I have a cast-iron stomach.

          Yes, the costs involved with medical cannabis can be high, but it depends on how much you use every day. High-CBD strains can help with inflammation and pain, and you won’t get “high” with those. (High-CBD strains are like strong aspirin, without the stomach upset.) If you were to choose an edible, you could just eat one a day and maybe your costs wouldn’t be so much. Depending on where you live, you can also get it in a liquid form, like drops, which would probably be the most cost-efficient product. I’m not trying to convince you to use cannabis, but if you don’t know anything about it, then you might not know all the different delivery methods that are now available.


        • I don’t know much about it and not even sure whether it is legal in my state or not. I don’t think so, but I never really checked. But if it is like taking strong aspirin it doesn’t seem like it helps much. Aspirin which I have to take every day for blood thinner 325 mg doesn’t do anything. Glad you don’t have to smoke it.

          Liked by 1 person

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