Abilify for Tourette’s in children?

http://www.fiercepharmaasia.com/story/japans-otsuka-sues-us-fda-over-abilify-unique-focus-exclusivity-rules/2015-03-26

Otsuka obtained 7-year exclusivity to market Abilify in December under the FDA’s orphan drug procedures, based on the Tourette pediatric indication. Up to now, Abilify had been earning Otsuka $6.5 [billion] a year as one of the leading antipsychotic drugs, including treatment for bipolar disorder and schizophrenia.

In an almost Kafkaesque twist and why Otsuka is upset, Abilify’s patent protection is set to expire April 20, opening it to generic competition. The orphan drug approval for treating Tourette’s was Otsuka’s way of keeping Abilify on the market as well as its new indication for an additional 7 years without a generic challenge…

The argument Otsuka laid out in the suit and what the court must determine is whether the agency can approve Abilify for a broader segment of the population when no clinical trials have been conducted to test its safety and effectiveness in treating Tourette’s in those age groups…

https://www.google.com/patents/US20120258971

This invention provides a novel therapeutic agent for chronic pain. The therapeutic agent for chronic pain comprises aripiprazole as an active ingredient…

http://www.medicalnewstoday.com/articles/248385.php

Abilify uses a different mechanism from other drugs that have been approved for the same symptoms. The majority of antipsychotics shut down dopamine receptors. Abilify works by making the receptors work properly…

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3184588/

Four Cases of Chronic Pain That Improved Dramatically Following Low-Dose Aripiprazole Administration (2011)

http://forums.prohealth.com/forums/index.php?threads/abilify-has-helped-my-fibromyalgia-a-lot.204793/

I just wanted to let you all know, I started taking abilify a couple of weeks ago for depression. However, it has helped my fibromyalgia so much I am off of the tramadol I have taken for 10 years! …

It is TERRIBLY expensive though. On the light side. If you will show a letter of denial from medicaid and your income is low, you can get it free through Astra Zenica…

(This posting is for information only.  I do not believe that anti-psychotics treat chronic pain.  But just like anti-depressants, they may help a very small number of pain patients.  It’s not a drug I would try, especially since I’ve tried almost every anti-depressant without benefit.  And I think the side effects occur a lot more frequently than advertised.)

More Awesome Women

http://the-daily.buzz/lawmaker-was-raped-had-abortion/?ts_pid=2

Lawmaker Says She’s “Sat Here Too Long,” Discloses That She Was Raped And Had An Abortion

This week, Ohio State Rep. Teresa Fedor (D) stood up during a legislative debate about a proposed abortion ban and revealed publicly for the first time that she had been sexually assaulted, became pregnant, and had an abortion…

“I dare any one of you to judge me,” she added. “I dare you to walk in my shoes.”

“I personally resent that women have to tell their deepest, darkest traumas in public, their most private moments in public, in order to get people to understand that these bills, these attempts to take away women’s rights, how devastating they are,” Rep. Victoria Steele, the Arizona lawmaker who disclosed her sexual assault earlier this month, told Cosmopolitan this month. “We should not have to bare that part of our lives in such a public way to be able to access legal medical care.”

Still, although Steele said “it was hard as hell to do what I did in that hearing,” she concluded that she didn’t regret it.