The visions of drugs and the visions of art don’t mix?
Never. The hallucinogens produce visionary states, sort of, but morphine and its derivatives decrease awareness of inner processes, thoughts, and feelings. They are painkillers, pure and simple. They are absolutely contraindicated for creative work, and I include in the lot alcohol, morphine, barbiturates, tranquilizers—the whole spectrum of sedative drugs. As for visions and heroin, I had a hallucinatory period at the very beginning of addiction, for instance, a sense of moving at high speed through space. But as soon as addiction was established, I had no visions—vision— at all and very few dreams.
Why did you stop taking drugs?
I was living in Tangier in 1957, and I had spent a month in a tiny room in the Casbah staring at the toe of my foot. The room had filled up with empty Eukodol cartons; I suddenly realized I was not doing anything. I was dying. I was just apt to be finished. So I flew to London and turned myself over to Dr. John Yerbury Dent for treatment. I’d heard of his success with the apomorphine treatment. Apomorphine is simply morphine boiled in hydrochloric acid; it’s nonaddictive. What the apomorphine did was to regulate my metabolism. It’s a metabolic regulator. It cured me physiologically. I’d already taken the cure once at Lexington, and although I was off drugs when I got out, there was a physiological residue. Apomorphine eliminated that. I’ve been trying to get people in this country interested in it, but without much luck. The vast majority—social workers, doctors—have the cop’s mentality toward addiction. A probation officer in California wrote me recently to inquire about the apomorphine treatment. I’ll answer him at length. I always answer letters like that.
Have you had any relapses? …
What about addicts?
Well, there will be a lot of morphine addiction. Remember that there were a great many addicts at that time. Jesse James was an addict. He started using morphine for a wound in his lung, and I don’t know whether he was permanently addicted, but he tried to kill himself. He took sixteen grains of morphine and it didn’t kill him, which indicates a terrific tolerance. So he must have been fairly heavily addicted…
Historically, apomorphine has been tried for a variety of uses including psychiatric treatment of homosexuality in the early 20th century, and more recently in treating erectile dysfunction. Currently, apomorphine is used in the treatment of Parkinson’s disease. It is a potent emetic (i.e., it induces vomiting) and should not be administered without an antiemetic such as domperidone. The emetic properties of apomorphine are exploited in veterinary medicine to induce therapeutic emesis in canines that have recently ingested toxic or foreign substances.
It was also successfully used as an unofficial treatment of heroin addiction, a purpose for which it was championed by the author William S. Burroughs. A recent study indicates that apomorphine might be a suitable marker for assessing central dopamine system alterations associated with chronic heroin consumption. There is, however, no clinical evidence that apomorphine is an effective and safe treatment regimen for opiate addiction. Early studies involved aversion therapy in alcoholism and anxiety, and modern reports are rather anecdotal.